Meroterpenes from Psoralea corylifolia against Pyricularia oryzae

Abstract

Six new meroterpenes, namely, 13-methoxyisobakuchiol (1), 13-ethoxyisobakuchiol (2), 12,13-dihydro-13-hydroxybakuchiol (3), Δ¹⁰-12,13-dihydro-12-(R,S)-methoxyisobakuchiol (4 and 5), and 15-demetyl-12,13-dihydro-13-ketobakuchiol (6), together with four known ones, namely, Δ³,2-hydroxybakuchiol (7), Δ¹,3-hydroxybakuchiol (8), bakuchiol (9), and Δ^1,3-bakuchiol (10), were isolated from the seeds of Psoralea corylifolia. Their structures were identified based on spectral data, including those obtained via 1D and 2D NMR, and MS spectral analyses. Antifungal screening results indicated that all compounds showed moderate inhibitory activities against Pyricularia oryzae.

Key words

Psoralea corylifolia - Fabaceae - meroterpenes - antifungal - Pyricularia oryzae

These authors contributed equally to this paper.

• References

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